Map of United States
, 1830–1835. Oklahoma is depicted in light yellow-green.
In 1830, a group of Indians collectively referred to as the
Five Civilized Tribes (the Cherokee, Chickasaw, Choctaw, Muscogee, and Seminole tribes) were living as
autonomous nations in what would be later called the American
Deep South. The process of cultural transformation, as proposed by
George Washington and
Henry Knox, was gaining momentum, especially among the Cherokee and Choctaw.
American settlers had been pressuring the federal government to remove Indians from the Southeast; many settlers were encroaching on Indian lands, while others wanted more land made available to white settlers. Although the effort was vehemently opposed by many, including U.S. Congressman
Davy Crockett of Tennessee,
President Andrew Jackson was able to gain Congressional passage of the
Indian Removal Act of 1830, which authorized the government to extinguish Indian title to lands in the Southeast.
In 1831, the Choctaw became the first Nation to be removed, and their removal served as the model for all future relocations. After two wars, many Seminoles were removed in 1832. The Creek removal followed in 1834, the Chickasaw in 1837, and lastly the Cherokee in 1838.
 Many Indians remained in their ancestral homelands; some Choctaw are found in Mississippi, Creek in Alabama and Florida, Cherokee in
North Carolina, and Seminole in Florida; a small group had moved to the Everglades and were never defeated by the United States government. A limited number of non-Indians, including some of African descent (some as slaves, and others as spouses or freedmen), also accompanied the Indians on the trek westward.
 By 1837, 46,000 Indians from the southeastern states had been removed from their homelands, thereby opening 25 million acres (100,000 km2) for predominantly white settlement.
Prior to 1830, the fixed boundaries of these autonomous
tribal nations, comprising large areas of the United States, were subject to continual cession and annexation, in part due to pressure from
squatters and the threat of military force in the newly declared U.S.
territories—federally administered regions whose boundaries supervened upon the Native treaty claims. As these territories became
U.S. states, state governments sought to dissolve the boundaries of the Indian nations within their borders, which were independent of state jurisdiction, and to expropriate the land therein. These pressures were exacerbated by U.S. population growth and the expansion of
slavery in the South, with the rapid development of cotton cultivation in the uplands following the invention of the
The removals, conducted under Presidents
Andrew Jackson and
Martin Van Buren, followed the
Indian Removal Act of 1830. The Act provided the President with powers to exchange land with Native tribes and provide infrastructure improvements on the existing lands. The law also gave the president power to pay for transportation costs to the West, should tribes choose to relocate. The law did not, however, allow the President to force tribes to move West without a mutually agreed-upon treaty.
In the years following the Act, the Cherokee filed several lawsuits regarding conflicts with the state of Georgia. Some of these cases reached the Supreme Court, the most influential being
Worcester v. Georgia (1832). Samuel Worcester and other non-Indians were convicted by Georgia law for residing in Cherokee territory in the state of Georgia, without a license. Worcester was sentenced to prison for four years and appealed the ruling, arguing that this sentence violated treaties made between Indian nations and the United States federal government by imposing state laws on Cherokee lands. The Court ruled in Worcester's favor, declaring that the Cherokee Nation was subject only to federal law and that the
Supremacy Clause barred legislative interference by the state of Georgia. Chief Justice Marshall argued, "The Cherokee nation, then, is a distinct community occupying its own territory in which the laws of Georgia can have no force. The whole intercourse between the United States and this Nation, is, by our constitution and laws, vested in the government of the United States."
Andrew Jackson did not listen to the Supreme Court mandate barring Georgia from intruding on Cherokee lands. He feared that enforcement would lead to open warfare between federal troops and the Georgia militia, which would compound the
ongoing crisis in South Carolina and lead to a broader civil war. Instead, he vigorously negotiated a land exchange treaty with the Cherokee.
 Political opponents
Henry Clay and
John Quincy Adams, who supported the Worcester decision, were outraged by Jackson's refusal to uphold Cherokee claims against the state of Georgia.
Ralph Waldo Emerson wrote an account of Cherokee assimilation into the American culture, declaring his support of the Worcester decision.
Jackson chose to continue with Indian removal, and negotiated The
Treaty of New Echota, on December 29, 1835, which granted Cherokee Indians two years to move to Indian Territory (modern Oklahoma). Only a fraction of the Cherokees left voluntarily. The U.S. government, with assistance from state militias, forced most of the remaining Cherokees west in 1838.
 The Cherokees were temporarily remanded in camps in eastern Tennessee. In November, the Cherokee were broken into groups of around 1,000 each and began the journey west. They endured heavy rains, snow, and freezing temperatures.
When the Cherokee negotiated the
Treaty of New Echota, they exchanged all their land east of the Mississippi for land in modern Oklahoma and a $5 million payment from the federal government. Many Cherokee felt betrayed that their leadership accepted the deal, and over 16,000 Cherokee signed a petition to prevent the passage of the treaty. By the end of the decade in 1840, tens of thousands of Cherokee and other tribes had been removed from their land east of the Mississippi River. The Creek, Choctaw, Seminole, and Chicksaw were also relocated under the Indian Removal Act of 1830. One Choctaw leader portrayed the removal as "A Trail of Tears and Deaths", a devastating event that removed most of the Native population of the southeastern United States from their traditional homelands.
forced relocations have sometimes been referred to as "
death marches", in particular with reference to the Cherokee march across the Midwest in 1838, which occurred on a predominantly land route.
Indians who had the means initially provided for their own removal. Contingents that were led by conductors from the U.S. Army included those led by
Edward Deas, who was claimed to be a sympathizer for the Cherokee plight.rounded into camps and pressed into oversized detachments, often over 700 in size (larger than the populations of
Little Rock or
Memphis at that time). Communicable diseases spread quickly through these closely quartered groups, killing many. These contingents were among the last to move, but following the same routes the others had taken; the areas they were going through had been depleted of supplies due to the vast numbers that had gone before them. The marchers were subject to extortion and violence along the route. In addition, these final contingents were forced to set out during the hottest and coldest months of the year, killing many. Exposure to the elements, disease and starvation, harassment by local frontiersmen, and insufficient rations similarly killed up to one-third of the Choctaw and other nations on the march.
The largest death toll from the Cherokee forced relocation comes from the period after the May 23, 1838 deadline. This was at the point when the remaining Cherokee were
There exists some debate among historians and the affected tribes as to whether the term "Trail of Tears" should be used to refer to the entire history of forced relocations from the United States east of the Mississippi into
Indian Territory (as was the stated U.S. policy), or to the
Five Tribes described above, to the route of the land march specifically, or to specific marches in which the remaining holdouts from each area were rounded up.