Stanozolol

Stanozolol
Stanozolol.svg
Estanozolol-3D.pngEstanozolol-3D-CPK.png
Clinical data
Trade namesMany[2]
SynonymsAndrostanazole; WIN-14833; NSC-43193; 17α-Methyl-2'H-androst-2-eno[3,2-c]pyrazol-17β-ol
AHFS/Drugs.comMultum Consumer Information
Pregnancy
category
  • X
Routes of
administration
By mouth, intramuscular injection (veterinary)[1]
Drug classAndrogen; Anabolic steroid
ATC code
Legal status
Legal status
Pharmacokinetic data
BioavailabilityHigh[4]
MetabolismLiver[3]
half-lifeOral: 9 hours[5]
IM: 24 hours (aq. susp.)[5][1]
Duration of actionIM: >1 week[3]
ExcretionUrine: 84%[citation needed]
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.030.801 Edit this at Wikidata
Chemical and physical data
FormulaC21H32N2O
Molar mass328.49 g/mol
3D model (JSmol)
  (verify)

Stanozolol, sold under many brand names, is an androgen and anabolic steroid (AAS) medication which was derived from dihydrotestosterone (DHT).[6][2][7] It was developed by American pharmaceutical company Winthrop Laboratories (Sterling Drug) in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the USA.[7][8] It is also used in veterinary medicine.[2][7] Stanozolol has mostly been discontinued, and remains available in only a few countries.[2][7] It is given by mouth in humans or by injection into muscle in animals.[7]

Unlike most injectable AAS, stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form.[7] The drug has a high oral bioavailability, due to a C17α alkylation which allows the hormone to survive first-pass liver metabolism when ingested.[7] It is because of this that stanozolol is also sold in tablet form.[7]

Stanozolol is one of the AAS commonly used as performance-enhancing drugs and is banned from use in sports competition under the auspices of the International Association of Athletics Federations (IAAF) and many other sporting bodies. Additionally, stanozolol has been used in US horse racing.[9]

Medical uses

Stanozolol has been used in both animals and human patients for a number of conditions. In humans, it has been demonstrated to be successful in treating anaemia and hereditary angioedema, the latter of which it has been specifically approved for the treatment of in some countries.[10] Veterinarians may prescribe the drug to improve muscle growth, red blood cell production, increase bone density and stimulate the appetite of debilitated or weakened animals.

Other Languages
български: Станозолол
català: Estanozolol
dansk: Stanozolol
Deutsch: Stanozolol
español: Estanozolol
Esperanto: Stanozololo
français: Stanozolol
italiano: Stanozololo
latviešu: Stanozolols
lietuvių: Stanozololas
magyar: Sztanozolol
Nederlands: Stanozolol
norsk: Stanozolol
português: Estanozolol
русский: Станозолол
српски / srpski: Stanozolol
srpskohrvatski / српскохрватски: Stanozolol
svenska: Stanozolol
中文: 康力龙