The Pame are an indigenous people of central Mexico living in the state of San Luis Potosí. They call themselves Xi'úi. They speak the Pame languages, which belong to the Oto-Pamean group of the Oto-Manguean language family.
According to some sources about the Chichimec Wars they were the least warlike of all the Chichimeca tribes.
Junípero Serra learned the Pame language and translated the catechism into Pame.