Gregg L. Semenza

Gregg L. Semenza
Born
Gregg Leonard Semenza

1956 (age 62–63)
EducationHarvard University (BA)
University of Pennsylvania (MD, PhD)
Known forHypoxia-inducible factors
Spouse(s)Laura Kasch-Semenza
AwardsAlbert Lasker Award for Basic Medical Research (2016)
Nobel Prize in Physiology or Medicine (2019)
Scientific career
InstitutionsJohns Hopkins School of Medicine
Molecular genetic analysis of the silent carrier of beta thalassemia (haplotype) (1984)
Doctoral advisorsElias Schwartz
Saul Surrey

Gregg Leonard Semenza (born 1956) is an American Nobel Laureate who is the professor of pediatrics, radiation oncology, biological chemistry, medicine, and oncology at the Johns Hopkins University School of Medicine. He serves as the director of the vascular program at the Institute for Cell Engineering.[1] He is a 2016 recipient of the Albert Lasker Award for Basic Medical Research.[2] He is known for his discovery of HIF-1, which allows cancer cells to adapt to oxygen-poor environments. He shared the 2019 Nobel Prize in Physiology or Medicine for "discoveries of how cells sense and adapt to oxygen availability" with William Kaelin Jr. and Peter J. Ratcliffe.[3][4]

Early life

Semenza was born in 1956[5] in Flushing, New York City and he and his four siblings grew up in Westchester County, New York.[6]

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