medicine, diuretics are used to treat
water poisoning, and certain
kidney diseases. Some diuretics, such as
acetazolamide, help to make the
alkaline and are helpful in increasing excretion of substances such as
aspirin in cases of
overdose or poisoning. Diuretics are often abused by those with
eating disorders, especially
bulimics, in attempts to lose weight.
antihypertensive actions of some diuretics (
loop diuretics in particular) are independent of their diuretic effect.
That is, the reduction in blood pressure is not due to decreased blood volume resulting from increased urine production, but occurs through other mechanisms and at lower doses than that required to produce diuresis.
Indapamide was specifically designed with this in mind, and has a larger therapeutic window for hypertension (without pronounced diuresis) than most other diuretics.