Signs and symptoms
An 1858 lithograph captioned 'Melancholy passing into mania'. In the past, persons with bipolar disorder could be consigned to an asylum.
Mania is the defining feature of bipolar disorder,
 and can occur with different levels of severity. With milder levels of mania, known as
hypomania, individuals are energetic, excitable, and may be highly productive.
 As hypomania worsens, individuals begin to exhibit erratic and impulsive behavior, often making poor decisions due to unrealistic ideas about the future, and sleep very reduced.
 At the extreme, manic individuals can experience distorted or delusional beliefs about the universe, hallucinate, hear voices, to the point of
 A depressive episode commonly follows an episode of mania.
 The biological mechanisms responsible for switching from a manic or hypomanic episode to a depressive episode, or vice versa, remain poorly understood.
An 1892 color lithograph depicting a woman diagnosed with hilarious mania.
Mania is a distinct period of at least one week of elevated or irritable
mood, which can range from euphoria to delirium, and those experiencing hypo- or mania may exhibit three or more of the following behaviors:
speak in a rapid, uninterruptible manner, short
racing thoughts, increased
goal-oriented activities, agitation, or they may exhibit behaviors characterized as impulsive or high-risk, such as
hypersexuality or excessive spending.
 To meet the definition for a manic episode, these behaviors must impair the individual's ability to socialize or work.
 If untreated, a manic episode usually lasts three to six months.
People with hypomania or mania may experience a decreased need of sleep, speak excessively in addition to speaking rapidly, and impaired judgment.
 Manic individuals often have a history of substance abuse developed over years as a form of "self-medication".
 At the more extreme, a person in a full blown manic state can experience
psychosis; a break with reality, a state in which thinking is affected along with mood.
 They may feel unstoppable, or as if they have been "chosen" and are on a "special mission", or have other grandiose or delusional ideas.
 This may lead to violent behavior and, sometimes, hospitalization in an inpatient
 The severity of manic symptoms can be measured by rating scales such as the
Young Mania Rating Scale, though questions remain about their reliability.
The onset of a manic (or depressive) episode is often foreshadowed by
 Mood changes,
psychomotor and appetite changes, and an increase in anxiety can also occur up to three weeks before a manic episode develops.
Hypomania is the milder form of mania, defined as at least four days of the same criteria as mania,
 but does not cause a significant decrease in the individual's ability to socialize or work, lacks psychotic features such as
delusions or hallucinations, and does not require psychiatric hospitalization.
 Overall functioning may actually increase during episodes of hypomania and is thought to serve as a defense mechanism against depression by some.
 Hypomanic episodes rarely progress to full blown manic episodes.
 Some people who experience hypomania show increased creativity
 while others are irritable or demonstrate poor judgment.
Hypomania may feel good to some persons who experience it, though most people who experience hypomania state that the stress of the experience is very painful.
 Bipolar people who go hypo, however, tend to forget the effects of their actions on those around them. Even when family and friends recognize mood swings, the individual will often deny that anything is wrong.
 What might be called a "hypomanic event", if not accompanied by depressive episodes, is often not deemed problematic, unless the mood changes are uncontrollable, volatile or mercurial.
 Most commonly, symptoms continue for a few weeks to a few months.
Symptoms of the
depressive phase of bipolar disorder include persistent feelings of sadness, irritability or anger, loss of interest in previously enjoyed activities, excessive or inappropriate guilt, hopelessness, sleeping too much or not enough, changes in appetite and/or weight, fatigue, problems concentrating, self-loathing or feelings of worthlessness, and thoughts of death or suicidal ideation.
 In severe cases, the individual may develop symptoms of
psychosis, a condition also known as severe bipolar disorder with psychotic features. These symptoms include
hallucinations. A major depressive episode persists for at least two weeks, and may result in suicide if left untreated.
The earlier the age of onset, the more likely the first few episodes are to be depressive.
 Because a bipolar diagnosis requires a manic or hypomanic episode, many patients are initially diagnosed and treated as having
major depression and then incorrectly prescribed antidepressants.
Mixed affective episodes
In bipolar disorder,
mixed state is a condition during which symptoms of both mania and depression occur simultaneously.
 Individuals experiencing a mixed state may have manic symptoms such as grandiose thoughts while simultaneously experiencing depressive symptoms such as excessive guilt or feeling suicidal.
 Mixed states are considered to be high-risk for suicidal behavior since depressive emotions such as hopelessness are often paired with
mood swings or
difficulties with impulse control.
Anxiety disorder occurs more frequently as a comorbidity in mixed bipolar episodes than in non-mixed bipolar depression or mania.
 Substance abuse (including alcohol) also follows this trend, thereby appearing to depict bipolar symptoms as no more than a consequence of substance abuse.
Associated features are clinical phenomena that often accompany the disorder but are not part of the diagnostic criteria. In adults with the condition, bipolar disorder is often accompanied by changes in
cognitive processes and abilities. These include reduced
executive capabilities and impaired
memory. How the individual processes the universe also depends on the phase of the disorder, with differential characteristics between the manic, hypomanic and depressive states.
 Some studies have found a significant association between bipolar disorder and
 Those with bipolar disorder may have difficulty in maintaining relationships. There are several common childhood precursors seen in children who later receive a diagnosis of bipolar disorder; these disorders include mood abnormalities, full major depressive episodes, and
attention deficit hyperactivity disorder (ADHD).
The diagnosis of bipolar disorder can be complicated by coexisting (comorbid) psychiatric conditions including the following:
eating disorders, attention deficit hyperactivity disorder,
premenstrual syndrome (including
premenstrual dysphoric disorder), or
 A careful longitudinal analysis of symptoms and episodes, enriched if possible by discussions with friends and family members, is crucial to establishing a treatment plan where these comorbidities exist.