Ashoka, the emperor of the Maurya Dynasty, ruled all of major parts of Bengal from ca. 269 BC to 232 BC. Being a devotee of Gautama Buddha, he propagated Buddhism across his kingdom which included Bikrampur to the east. Following the high ideals of this religion, Pala Kings came to Bikrampur to rule the region.
The second ruler of Pala Empire, Dharmapal, built a Buddhist monastery in Bikrampur during his reign in 770–810. After his death, his son, Devapala ruled this area until 850 CE. Then the region is successively ruled by Vigrahapala I, Narayanapala, Rajyapala, Gopala II, Vigrahapala II, Mahipala, Naya Pala, Vigrahapala III, Mahipala II, Shurapala II, Ramapala, Kumarapala, Gopala III and Madanapala. Pala empire disintegrated in 1174 weakened by attacks of the Sena dynasty.
During the rule of Srichandra (reigned 930 – 975 AD), the administrative centre of the Chandra kingdom was established at Bikrampur.
A copper-plate inscription from the time of the ruler Vijay Sen (ruled 1097–1160), founder of Sen dynasty, was found in Barrackpore, in 1911. In this inscription, Bikrampur was mentioned as the capital of that region. It continued to be the capital throughout the, Sena Dynasty. In 1205, Turkic invader Bakhtiyar Khalji defeated the then-ruler Lakshman Sen in Nadia. Lakshman fled to Bikrampur. His two sons Vishwarup Sen and Keshab Sen kept ruling from here until 1230. But the copper-plate inscriptions during their reign do not mention Bikrampur as the capital.
Another Hindu ruler, Danuj Rai, defeated a successor of Keshab Sen and started ruling from here. In early 1280 he moved the capital to Suvarnagrama (later named Sonargaon).
Emperor Akbar established Bikrampur as one of the 52 parganas of Sonargaon sarkar in Bengal subah during his administrative reforms in 1572–1580. During his time, Chand Rai and Kedar Rai were the Zamindars of Bikramapur. In the expeditions against Bara-Bhuiyans, Mughal Subahdar Man Singh killed Kedar Rai in early 1600s.
In post-Aurangzeb era, during the time of Nawab Murshid Quli Khan, Bikrampur was divided into eight taluks – Bhagyakul, Sreenagar, Maijpara, Sinhapara, Taltala, Sirajdikhan, Louhojong and Baligaon. Each taluk was represented by one Zamindar. Muhammad Azim Khan became the Zamindar of Louhajong who held the title of "Khan Bahadur". Gobinda Prasad Roy became the Zamindar of Maijpara.