One hundred of the 105 passengers and crew on a United Arab Airlines flight, most of them Muslim pilgrims returning to Aswan from Mecca, are killed when the Ilyushin-18 turboprop crashes during a sandstorm.
June 3 – While operating at sea on SEATO maneuvers, the Australian aircraft carrier HMAS Melbourne accidentally rams and slices into the American destroyer USS Frank E. Evans in the South China Sea, killing 74 American seamen.
Football War: After Honduras loses a soccer game against El Salvador, rioting breaks out in Honduras against Salvadoran migrant workers. Of the 300,000 Salvadoran workers in Honduras, tens of thousands are expelled, prompting a brief Salvadoran invasion of Honduras. The OAS works out a cease-fire on July 18, which takes effect on July 20.
July 20 – Apollo program: The lunar module Eagle | Apollo 11 lands on the lunar surface. An estimated 500 million people worldwide watch in awe as Neil Armstrong takes his historic first steps on the Moon at 10:56 pm ET (02:56 UTC July 21), the largest television audience for a live broadcast at that time.
The Apollo 11 astronauts return from the first successful Moon landing, and are placed in biological isolation for several days, on the chance they may have brought back lunar germs. The airless lunar environment is later determined to preclude microscopic life.
July 25 – Vietnam War: U.S. President Richard Nixon declares the Nixon Doctrine, stating that the United States now expects its Asian allies to take care of their own military defense. This starts the "Vietnamization" of the war.
August 4 – Vietnam War: At the apartment of French intermediary Jean Sainteny in Paris, U.S. representative Henry Kissinger and North Vietnamese representative Xuan Thuy begin secret peace negotiations. They eventually fail since both sides cannot agree to any terms.
August 17 – Category 5 Hurricane Camille, the most powerful tropical cyclonic system at landfall in history, hits the Mississippi coast, killing 248 people and causing US$1.5 billion in damage (1969 dollars).
September 14 – Persons who were born during the years from 1944 to 1951, and who celebrate their birthdays on this day, mark the occasion without being aware that September 14 will be the first date selected in the new U.S. draft lottery on December 1.
October 2 – A 1.2 megaton thermonuclear device is tested at Amchitka Island, Alaska. This test is code-named Project Milrow, the 11th test of the Operation Mandrel 1969–1970 underground nuclear test series. This test is known as a "calibration shot" to test if the island is fit for larger underground nuclear detonations.
November 9 – A group of American Indians, led by Richard Oakes, seizes Alcatraz Island as a symbolic gesture, offering to buy the property for $24 from the U.S. government. A longer occupation begins 11 days later. The act inspires a wave of renewed Indian pride and government reform.
U.S. President Richard Nixon and Japanese Premier Eisaku Satō agree in Washington, D.C. to the return of Okinawa to Japanese control in 1972. Under the terms of the agreement, the U.S. retains rights to military bases on the island, but they must be nuclear-free.
The first ARPANET link is established (the progenitor of the global Internet).
December 1 – Vietnam War: The first draft lottery in the United States since World War II is held. September 14 is the first of the 366 days of the year selected, meaning that those persons who were born on September 14 in the years from 1944 to 1951 would be the first to be summoned. On January 4, 1970, The New York Times will run a long article, "Statisticians Charge Draft Lottery Was Not Random".
December 2 – The Boeing 747 jumbo jet makes its first passenger flight. It carries 191 people, most of them reporters and photographers, from Seattle to New York City.
The Altamont Free Concert is held at the Altamont Speedway in northern California. Hosted by The Rolling Stones, it is an attempt at a "Woodstock West" and is best known for the uproar of violence that occurred. It is viewed by many as the "end of the sixties."